Introduction

Sodium thiosulfate, 5% solution is a component of special kits, such as Reticulin and Reticulin contrast, Masson Fontana, Von Kossa, Movat and Verhoeff kits. These are special kits used to detect argentophilic and argentaffin fibers in histology samples. Sodium thiosulfate solution’s role is rinsing and removing unbound silver after using silver nitrate solution on the sample.